Specific Targeting of Oncogenes Using CRISPR Technology
نویسندگان
چکیده
منابع مشابه
Generation of global Spata19 knockout mouse using CRISPR/Cas9 nickase technology
Introduction: SPATA19 gene is expressed in developmental stages of testis and some organs, but so far its function has only been examined in the testis. In this study, we provided an effective pathway for the generation of these mice using new CRISPR / Cas9 nickase method while generating Spata19 knockout mice for future studies in other organs. Materials and Methods: CRISPR / Cas9 nickase plas...
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ژورنال
عنوان ژورنال: Cancer Research
سال: 2018
ISSN: 0008-5472,1538-7445
DOI: 10.1158/0008-5472.can-18-0571